Back in the 1970s when many of us were struggling to free ourselves from mainframes, the mantra in the computing world was "Nobody ever got fired for choosing IBM." No doubt Bill Gates was inspired by this to build his own empire. Today, people unblushingly swap "IBM" for "Microsoft" in that mantra.
Since converting back to the Macintosh I've been learning a lot about Microsoft-centric software. Several programs that ran on both systems have essentially withered, especially since the conversion to OS X. I'm most directly affected by Microsoft-centric teams at Intuit and at Adobe.